Lancaster was served by the Houston & Texas Central (H&TC) Railway owned by Southern Pacific, the Missouri - Kansas - Texas ("Katy") Railroad, and the Texas Electric Railway.
This building appears
to be either a relic of the final H&TC depot in Lancaster or more likely, an
adjacent freight house. Either way, it's probably been heavily modified.
Historic aerial imagery shows the building at this location, very close to (and
perhaps "on") the site of the H&TC depot, at least as early as 1956, only 22
years after the Lancaster branch was abandoned. North 2nd St. is barely visible
at far right, and the utility pole in the distance is adjacent to the BNSF
(ex-Katy) tracks. Whether the building's structural heritage dates to the H&TC
era, and if so, the extent of the modifications, is unknown. The building was
razed or removed not long after this photo was taken. (Jim King, 2005)
Katy depot, Google Street View, Feb. 2021
Texas Electric Railway depot, Google Street View, Feb. 2021